About the Library
RenMab™ KO Library
The RenMab™ KO library contains a list of RenMab™ mice each with a specific target gene knocked out. These mice are designed to establish robust immune response and generate antibodies that bind to more epitopes of target protein including conserved domains.
Applications of RenMab™ KO mouse include:
• Antibody discovery against challenging targets such as protein with high homology between human and mouse or GPCR/ion channel proteins.
• Surrogate antibody generation.
• Multiple epitope recognition from the same target protein.
Phase Overview of KO Targets Progress