Search Knockouts
-
Cardiovascular
- Target Name
-
mouse models
- RenMab™
- RenLite™
- Launched Drugs
G-CSFR
93
AGTR1
49
TNF
46
5HT2AR
24
CD20
22
FVIII
9
IL6
5
IL1B
4
IL6R
3
VWF
2
Inflammation and Autoimmunity
- Target Name
-
mouse models
- RenMab™
- RenLite™
- Launched Drugs
UPA
2
PGF
2
KLKB1
2
ITGAL
2
IL5
2
IL1R
2
CD80
2
CD22
2
CD10
2
C5a
2
Oncology
- Target Name
-
mouse models
- RenMab™
- RenLite™
- Launched Drugs
AXL
2
TYRO3
1
TROP2
1
TLR3
1
TLR2
1
SLAMF7
1
SIRPɑ
1
RANKL
1
Nectin-4
1
NCL
1
Others
- Target Name
-
mouse models
- RenMab™
- RenLite™
- Launched Drugs
MSP1R
1
MMP-9
1
MC4R
1
MAPT
1
IL3RA
1
IL1A
1
HRH3
1
CD62P
1
CD54
1
CD52
1
Gastrointestinal
- Target Name
-
mouse models
- RenMab™
- RenLite™
- Launched Drugs
CD2
1
TREM2
0
TNFSF15
0
TNFRSF1A
0
OX40
0
NKG2D
0
NKG2D
0
KLK5
ITGB7
0
IL20R1
Infectious Diseases
- Target Name
-
mouse models
- RenMab™
- RenLite™
- Launched Drugs
IL18RA
0
IL18
0
IL15
0
IL13
0
IL11
0
IL10RA
0
IL10
0
HAMP
0
GRP
0
GM-CSF
0
Metabolism
- Target Name
-
mouse models
- RenMab™
- RenLite™
- Launched Drugs
GITRL
GIPR
0
GIP
0
GHRL
0
GDF8
0
FSTL3
FGF21
0
FFAR1
0
EREG
0
CXCL14
Neuroscience
- Target Name
-
mouse models
- RenMab™
- RenLite™
- Launched Drugs
CXCL13
CX3CL1
0
CSPG5
CRCP
CLEC14A
CGRP
0
CFI
CD62E
0
CD56
0
CD18
0
Ophthalmology
- Target Name
-
mouse models
- RenMab™
- RenLite™
- Launched Drugs
CD160
CD133
0
CCR7
0
CCL11
0
APLNR
0
APLN
4-1BB
0
Orthopaedic Disorders
- Target Name
-
mouse models
- RenMab™
- RenLite™
- Launched Drugs
TNF
46
CD20
22
IL6
5
FGFR3
5
IL1B
4
IL6R
3
KLKB1
2
IL1R
2
Sclerostin
1
RANKL
1
Urological Diseases
- Target Name
-
mouse models
- RenMab™
- RenLite™
- Launched Drugs
MIF
1
FGF23
1
CD6
1
BAFF
1
TIMP2
TGM2
0
TEM1
0
SPP1
0
SIGLEC15
0
RAGE
0