Search Knockouts
-
Cardiovascular
- Target Name
-
mouse models
- RenMab™
- RenLite™
- Launched Drugs
G-CSFR
100
TNF
51
AGTR1
51
5HT2AR
26
CD20
23
FVIII
8
IL6
5
IL1B
5
PCSK9
3
KLKB1
3
Inflammation and Autoimmunity
- Target Name
-
mouse models
- RenMab™
- RenLite™
- Launched Drugs
IL6R
3
IL17A
3
CD38
3
VAP-1
2
UPA
2
PGF
2
IL5
2
IL23A
2
IL1R
2
IFNB1
2
Oncology
- Target Name
-
mouse models
- RenMab™
- RenLite™
- Launched Drugs
HCRTR1
2
FGFR4
2
FGF2
2
EPHA2
2
CD86
2
CD80
2
CD22
2
CD10
2
CB1
2
BAFF
2
Others
- Target Name
-
mouse models
- RenMab™
- RenLite™
- Launched Drugs
RANKL
1
MSP1R
1
MAPT
1
IL3RA
1
IL1A
1
HRH3
1
CD62P
1
CD54
1
CD52
1
CD33
1
Gastrointestinal
- Target Name
-
mouse models
- RenMab™
- RenLite™
- Launched Drugs
TNFSF15
0
TNFRSF1A
0
OX40
0
NKG2D
0
nk
KLK5
ITGB7
0
IL20R1
IL18RA
0
IL15
0
Infectious Diseases
- Target Name
-
mouse models
- RenMab™
- RenLite™
- Launched Drugs
IL11
0
IL10RA
0
IL10
0
HAMP
0
GRP
0
GM-CSF
0
GITR
0
GARP
0
FSTL1
FGL2
Metabolism
- Target Name
-
mouse models
- RenMab™
- RenLite™
- Launched Drugs
FGF21
0
FFAR1
0
EREG
0
CXCL14
CXCL10
0
CLEC14A
CHRDL1
CHI3L1
CGRP
0
CD5
0
Neuroscience
- Target Name
-
mouse models
- RenMab™
- RenLite™
- Launched Drugs
CD18
0
CD14
0
CD11d
CADM3
C6
0
C2
C1S
0
BACE
0
AQP4
0
APOE4
0
Ophthalmology
- Target Name
-
mouse models
- RenMab™
- RenLite™
- Launched Drugs
APLNR
0
APLN
ANGPT2
0
4-1BB
0
Orthopaedic Disorders
- Target Name
-
mouse models
- RenMab™
- RenLite™
- Launched Drugs
TNF
51
CD20
23
FGFR3
7
IL6
5
IL1B
5
KLKB1
3
IL6R
3
IL1R
2
Sclerostin
1
RANKL
1
Urological Diseases
- Target Name
-
mouse models
- RenMab™
- RenLite™
- Launched Drugs
PAI-1
1
MIF
1
FGF23
1
CD6
1
APRIL
1
TLR2
0
TIMP2
TGM2
0
TEM1
0
SPP1
0