ADORA2A

Synonyms

Adenosine receptor A2a, ADORA2A, Adenosine A2a Receptor, ADORA2, Adenosine Receptor Subtype A2a, A2aR, RDC8, Receptor, Adenosine A2A,

Description

Adenosine A2a receptor, also known as ADORA2A, is an adenosine receptor. The activity of this receptor is mediated by G proteins which activate adenylyl cyclase.

KO Status

F0

Drug Information

Launched drugs: 13
Drugs in clinical trials: 16
Latest Research Phase:Approved

Drug Name

Code

Phase

Company

Indications

Clinical Trials

Aminophenazone/Caffeine

Approved

Fever

Sodium Benzoate/Caffeine

Approved

Central Nervous System Diseases

Aspirin/Butalbital/Caffeine

Approved

Headache

Oxtriphylline

Approved

Asthma

Aspirin/Caffeine/Dihydrocodeine Tartrate

Withdrawn

Sun Pharmaceutical

Pain

Regadenoson Hydrate

CVT-3146

Approved

Astellas

Myocardial Ischemia, Coronary Artery Disease, Heart Diseases, Contrast agents

Aspirin/Caffeine/Codeine Phosphate/Butalbital

Approved

Allergan

Headache

Acetaminophen/Chlorphenamine Maleate/Methylephedrine Hydrochloride/Sulfogaiacol/Caffeine

Approved

Caffeine/Metamizole Sodium/Dihydroergotamine Mesylate

Approved

Migraine Disorders

Caffeine/Ergotamine Tartrate

Approved

Novartis Pharma Ag

Migraine Disorders

Antipyrine/Caffeine/Citric Acid

Approved

Sedation

Caffeine

Approved

Sleepiness, Consciousness, Fatigue, Mental Fatigue

Istradefylline

KW-6002

Approved

Kyowa Hakko Kirin Co Ltd

Substance-Related Disorders, Restless Legs Syndrome, Sleep Wake Disorders, Parkinson Disease, Hepatic Insufficiency, Movement Disorders

Antipyrine/Caffeine

Approved

Common Cold

Aminophenazone/Acetaminophen/Caffeine/Chlorphenamine Maleate

Approved

Common Cold

Aspirin/Caffeine/Acetaminophen

Approved

Anesthesia

Aspirin/Caffeine

Approved

Common Cold

Acetaminophen/Butalbital/Caffeine

Brompheniramine Maleate/Bromhexine Hydrochloride/Caffeine/Acetaminophen/Phenylephrine Hydrochloride

Approved

Common Cold

Acetaminophen/Caffeine

Zentiva