CD52

Synonyms

CD52 Antigen (CAMPATH-1 Antigen), Epididymal Secretory Protein E5, He5, CDW52 Antigen (CAMPATH-1 Antigen), CD52 Antigen, HEL-S-171mP, EDDM5, CD52, CDw52, Cambridge pathology 1 antigen, Human epididymis-specific protein 5, CAMPATH-1 antigen, CD52 Molecule, Epididymis Secretory Sperm Binding Protein Li 171mP

Description

CAMPATH-1 antigen, also known as cluster of differentiation 52 (CD52), is a glycoprotein that in humans is encoded by the CD52 gene. It may play a role in carrying and orienting carbohydrate, as well as having a more specific role.

KO Status

F2 (-/-)

Drug Information

Launched drug: 1
Drugs in clinical trials: 2
Latest Research Phase: Approved

Drug Name

Code

Phase

Company

Indications

Clinical Trials

Alemtuzumab

LDP-03, GZ-402673

Approved

Genzyme Corp, Bayer Ag

Hematologic Neoplasms, Graft vs Host Disease, Multiple Sclerosis, Lymphoma, Non-Hodgkin, Leukemia, Lymphocytic, Chronic, B-Cell

ALLO-647

ALLO-647

Phase 2 Clinical

Allogene Therapeutics Inc

Lymphoma, B-Cell, Carcinoma, Renal Cell, Multiple Myeloma, Lymphoma, Follicular, Lymphoma, Non-Hodgkin

Alemtuzumab biosimilar (Zhangjiang Biotechnology)

Phase 2 Clinical

Shanghai Zhangjiang Biotechnology Co Ltd

Leukemia, Lymphocytic, Chronic, B-Cell

Recombinant anti-CD52 humanized monoclonal antibody (Lanzhou Institute Of Biological Products/Shanghai Taiyin Biotechnology)

Phase 1 Clinical

Lanzhou Institute Of Biological Products Co Ltd, Shanghai Taiyin Biotechnology Co Ltd

Leukemia, B-Cell, Lymphoma, Non-Hodgkin, Leukemia, Prolymphocytic, T-Cell, Lymphoma, Leukemia, Lymphocytic, Chronic, B-Cell, Leukemia, Prolymphocytic

Campath-1G

Discontinued

University Of Cambridge

Graft vs Host Disease, Rejection of organ transplantation

Recombinant anti-CD52 humanized monoclonal antibody (Hisun Pharm)

Discontinued

Zhejiang Hisun Pharmaceutical Co Ltd

Leukemia, Lymphocytic, Chronic, B-Cell

GZ-402668

GLD-52, GZ-402668

Discontinued

Genzyme Corp

Multiple Sclerosis, Multiple Sclerosis, Chronic Progressive