About the HiTS Platform

RenMice® HiTS Platform

The RenMice® HiTS (Hyperimmune Target Specific) Platform consists of a library of RenMice® each with a specific target gene knocked out. These mice are designed to establish robust immune responses and generate antibodies that bind to more epitopes of the target protein, including conserved domains.

Applications of the RenMice® HiTS Platform include:
• Antibody discovery against challenging targets, such as proteins with high homology between human and mouse, or GPCR/ion channel proteins.
• Surrogate antibody generation.
• Multiple epitope recognition from the same target protein.

Ready to learn more about licensing opportunities and antibodies available for your target?

Phase Overview as of June 30, 2023, Partnerships as of June 30, 2023.

Phase Overview of RenMab™ Progress

Phase Overview of RenLite® Progress


Under Ongoing Partnership