ALB

Synonyms

Serum Albumin, PRO0883, ALB, PRO1341, HSA, Albumin, PRO0903,

Description

Binds water, Ca, Na, K, fatty acids, hormones, bilirubin and drugs (Probable). Its main function is the regulation of the colloidal osmotic pressure of blood (Probable). Major zinc transporter in plasma, typically binds about 80% of all plasma zinc . Major calcium and magnesium transporter in plasma, binds approximately 45% of circulating calcium and magnesium in plasma. Potentially has more than two calcium-binding sites and might additionally bind calcium in a non-specific manner. The shared binding site between zinc and calcium at residue Asp-273 suggests a crosstalk between zinc and calcium transport in the blood. The rank order of affinity is zinc > calcium > magnesium. Binds to the bacterial siderophore enterobactin and inhibits enterobactin-mediated iron uptake of E.coli from ferric transferrin, and may thereby limit the utilization of iron and growth of enteric bacteria such as E.coli . Does not prevent iron uptake by the bacterial siderophore aerobactin .

KO Status

F1 (+/-)

Drug Information

Launched drugs: 0
Drugs in clinical trials: 8
Latest Research Phase:Approved

Drug Name

Code

Phase

Company

Indications

Clinical Trials

Albumin Human(Sanquin Plasma Products)

Approved

Sanquin Plasma Products

Human Albumin(Huhan Nanyue)

Approved

Hunan Ziguang Huhan Nanyue Pharmaceutical Co Ltd

Human Serum Albumin (Green Cross)

Approved

Green Cross (China) Biological Products Co Ltd

Hypovolemia

Human albumin(Tonrol Bio-Pharmaceutical)

Approved

Tonrol Bio-Pharmaceutical Co Ltd

Hypovolemia

20% Human albumin (Hemarus Therapeutics)

Approved

Hemarus Therapeutics

Hypovolemia, Respiratory Distress Syndrome, Adult, Hypoalbuminemia, Nephrotic Syndrome

Human Albumin(Hangzhou Tigermed)

Hangzhou Tigermed Consulting Co Ltd

Albumin Human(Cis Bio International)

Approved

Cis Bio International Sa

Human albumin (Hebei Da'an Pharmaceutical)

Approved

Hebei Daan Pharmaceutical Co Ltd

Fibrosis, Respiratory Distress Syndrome, Adult, Shock, Hemorrhagic

Human Albumin (SK Plasma)

Approved

Sk Plasma

Albumin Human (Biotest Pharma GmbH)

Approved

Biotest Pharma Gmbh

Hypovolemia

Human Serum Albumin (Baxter)

IND

Baxter Ag, Baxter Manufacturing Spa, Wutian (China) International Trade Co Ltd

Human Albumin(Anhui Da'An)

Approved

Anhui Da'An Biological Products Pharmaceutical Co Ltd

Human albumin (Guizhou Taibang Biological Products)

Approved

Guizhou Taibang Biological Products Co Ltd

Fibrosis, Respiratory Distress Syndrome, Adult, Shock, Hemorrhagic

Human albumin (Guangdong Danxia Biopharm)

Approved

Guangdong Danxia Biopharmaceutical Co Ltd

Hypovolemia, Hemorrhage, Anemia, Hemolytic, Autoimmune, Hypoalbuminemia

Human Albumin(Guangdong Danxia)

Approved

Guangdong Danxia Biopharmaceutical Co Ltd

Hypovolemia

Vialebex (LFB SA/Swedish Orphan Biovitrum AB)

Approved

Lfb Biotechnologies, Swedish Orphan Biovitrum

Hypotension, Shock

Human albumin (Hualan Biological Engineering)

Approved

Hualan Genetic Engineering Co Ltd

Hypovolemia, Hemorrhage, Anemia, Hemolytic, Autoimmune, Hypoalbuminemia

89 Zirconium labeled GSK-3128349

Pending

Glaxosmithkline Plc

Drug-Related Side Effects and Adverse Reactions