CCR7

Synonyms

C-C CKR-7, CDw197, CD197, CCR-7, Epstein-Barr virus-induced G-protein coupled receptor 1, MIP-3 beta receptor, BLR2, EBI1, CC-CKR-7, EBV-induced G-protein coupled receptor 1, C-C Motif Chemokine Receptor 7, CC Chemokine Receptor 7, Lymphocyte-Specific G Protein-Coupled Peptide Receptor, Bukitt'S Lymphoma Receptor 2, EBV-Induced G Protein-Coupled Receptor 1, CD197 Antigen, Chemokine (C-C Motif) Receptor 7, CMKBR7, Epstein-Barr Virus Induced Gene 1, EVI1

Description

C-C chemokine receptor type 7 is a protein that in humans is encoded by the CCR7 gene.Receptor for the MIP-3-beta chemokine. Probable mediator of EBV effects on B-lymphocytes or of normal lymphocyte functions.Two ligands have been identified for this receptor: the chemokines (C-C motif) ligand 19 (CCL19/ELC) and (C-C motif) ligand 21 (CCL21) Receptor for the MIP-3-beta chemokine. Probable mediator of EBV effects on B-lymphocytes or of normal lymphocyte functions.

KO Status

RenMab: Immunization

Drug Information

Drug Name

Code

Phase

Company

Indications

Clinical Trials

anti-ILT3 CAR-T(Carbiogene)

Nidanilimab

CAN-04

Phase 2 Clinical

Lund University Foundation

Squamous Cell Carcinoma of Head and Neck, Pancreatic Neoplasms, Triple Negative Breast Neoplasms, Carcinoma, Transitional Cell, Breast Neoplasms, Colorectal Neoplasms, Carcinoma, Pancreatic Ductal, Carcinoma, Non-Small-Cell Lung, Melanoma

HLX-71

HLX-71, SI-F019

Phase 1 Clinical

Hengenix Biotech Inc

Coronavirus Disease 2019 (COVID-19)

IO-202

IO-202

Phase 1 Clinical

Leukemia, Myelomonocytic, Chronic, Leukemia, Myeloid, Acute

GSK3903371

GSK3903371

Clinical

Glaxosmithkline Plc

Neoplasms

NKp46 NKCE

NKp46-NKCE, NKp46 NKCE

Preclinical

Neoplasms

SAR-443579

SAR-443579, SAR443579, IPH6101, IPH-6101

Preclinical

Neoplasms

BI-1910

BI-1910

Preclinical

Bioinvent International

Solid tumours

IPR-1110

IPR 1110

Preclinical

Neoplasms

MNPR-101

huATN-658, ATN-291 F(ab’)2

Preclinical

Monopar Therapeutics Inc

Neoplasms