CD48

Synonyms

Signaling lymphocytic activation molecule 2, BCM1 surface antigen, CD48, BCM1, CD48 Molecule, CD48 Antigen (B-Cell Membrane Protein), B-Lymphocyte Activation Marker BLAST-1, SLAM Family Member 2, CD48 Antigen, BLAST1, SLAMF2, TCT.1, MEM-102, BLAST, HCD48, MCD48, Leukocyte antigen MEM-102,

Description

Cluster of differentiation 48 (CD48) also known as B-lymphocyte activation marker (BLAST-1) or signaling lymphocytic activation molecule 2 (SLAMF2) is a protein that in humans is encoded by the CD48 gene. CD48 is a member of the CD2 subfamily of the immunoglobulin superfamily (IgSF) which includes SLAM (signaling lymphocyte activation molecules) proteins, such as CD84, CD150, CD229 and CD244. CD48 is found on the surface of lymphocytes and other immune cells, dendritic cells and endothelial cells, and participates in activation and differentiation pathways in these cells.

KO Status

F0

Drug Information

Launched drug: 1
Drugs in clinical trials: 0
Latest Research Phase:Phase 1 Clinical

Drug Name

Code

Phase

Company

Indications

Clinical Trials

SGN-CD48A

SGN-CD48A

Phase 1 Clinical

Seattle Genetics

Multiple Myeloma

Anti-CD48 monoclonal antibody WM-63

Pending

Nonindustrial Source

Leukemia, Lymphocytic, Chronic, B-Cell