CD48
Synonyms
Signaling lymphocytic activation molecule 2, BCM1 surface antigen, CD48, BCM1, CD48 Molecule, CD48 Antigen (B-Cell Membrane Protein), B-Lymphocyte Activation Marker BLAST-1, SLAM Family Member 2, CD48 Antigen, BLAST1, SLAMF2, TCT.1, MEM-102, BLAST, HCD48, MCD48, Leukocyte antigen MEM-102,Description
Cluster of differentiation 48 (CD48) also known as B-lymphocyte activation marker (BLAST-1) or signaling lymphocytic activation molecule 2 (SLAMF2) is a protein that in humans is encoded by the CD48 gene. CD48 is a member of the CD2 subfamily of the immunoglobulin superfamily (IgSF) which includes SLAM (signaling lymphocyte activation molecules) proteins, such as CD84, CD150, CD229 and CD244. CD48 is found on the surface of lymphocytes and other immune cells, dendritic cells and endothelial cells, and participates in activation and differentiation pathways in these cells.
KO Status
F0
Drug Information
Launched drug: 1
Drugs in clinical trials: 0
Latest Research Phase:Phase 1 Clinical
Drug Name
Code
Phase
Company
Indications
Clinical Trials
SGN-CD48A
SGN-CD48A
Phase 1 Clinical
Seattle Genetics
Multiple Myeloma
Anti-CD48 monoclonal antibody WM-63
Pending
Nonindustrial Source
Leukemia, Lymphocytic, Chronic, B-Cell