GLP2R

Synonyms

Epididymis Secretory Sperm Binding Protein, GLP2R, Glucagon-like peptide 2 receptor, Glucagon Like Peptide 2 Receptor, GLP-2 Receptor, GLP-2-R, GLP-2R, Glucagon-Like Peptide-2 Receptor

Description

GLP2R (Glucagon-like peptide 2 receptor) is a receptor for glucagon-like peptide 2. The activity of this receptor is mediated by G proteins which activate adenylyl cyclase.

KO Status

RenMab: F2 (-/-)

Drug Information

Launched drug: 1
Drugs in clinical trials: 7
Latest Research Phase: Approved

Drug Name

Code

Phase

Company

Indications

Clinical Trials

Teduglutide

SHP-633, ALX-0600, [Gly2]GLP-2

Approved

Shire Development Llc

Kidney Diseases, Short Bowel Syndrome, Hepatic Insufficiency, Crohn Disease, Malabsorption Syndromes

Glepaglutide

ZP-1848

Phase 3 Clinical

Zealand Pharma

Inflammatory Bowel Diseases, Kidney Diseases, Short Bowel Syndrome

Apraglutide

FE-203799

Phase 3 Clinical

Ferring Bv

Hodgkin Disease, Short Bowel Syndrome, Renal Insufficiency, Chronic, Lymphoma, Non-Hodgkin

HM-15912

HM-15910, HM-15912

Phase 2 Clinical

Hanmi Pharmaceutical Co Ltd

Short Bowel Syndrome

Elsiglutide

ZP-1846

Phase 2 Clinical

Zealand Pharma A/S

Diarrhea

GX-G8

GX-G8

Phase 1 Clinical

Genexine Inc

Short Bowel Syndrome

SHP-681

SHP-681, TAK-681

Phase 1 Clinical

Shire

Short Bowel Syndrome

ZP-7570

ZP-7570

Phase 1 Clinical

Zealand Pharma A/S

Short Bowel Syndrome

NB-1002

NB-1002

Preclinical

Amunix

Gastrointestinal Diseases, Short Bowel Syndrome

Teduglutide(Meters Biopharma)

NM-003

Preclinical

Gastrointestinal Diseases