GRP

Synonyms

GRP, Gastrin-releasing peptide, Gastrin Releasing Peptide, Neuromedin C, Prepro-GRP, Bombesin, Pre-Progastrin Releasing Peptide, Testicular Tissue Protein Li 103, PreproGRP, GRP-10, ProGRP, BN

Description

Gastrin-releasing peptide is a neuropeptide, a regulatory molecule that has been implicated in a number of physiological and pathophysiological processes. Most notably, GRP stimulates the release of gastrin from the G cells of the stomach.Stimulates the release of gastrin and other gastrointestinal hormones. Contributes to the perception of prurient stimuli and to the transmission of itch signals in the spinal cord that promote scratching behavior. Contributes primarily to nonhistaminergic itch sensation. Contributes to long-term fear memory, but not normal spatial memory. Contributes to the regulation of food intake.

KO Status

RenMab: F0

Drug Information

Drug in clinical trials: 1
Latest Research Phase: Phase 2 Clinical

Drug Name

Code

Phase

Company

Indications

Clinical Trials

68Ga-NeoBOMB1

67Ga-NeoBOMB1, 68Ga-NeoBOMB1

Phase 2 Clinical

National Center For Scientific Research Demokritos, Erasmus Universiteit Rotterdam

Small Cell Lung Carcinoma, Neoplasms, Prostatic Neoplasms, Breast Neoplasms, Colorectal Neoplasms, Gastrointestinal Stromal Tumors, Carcinoma, Non-Small-Cell Lung

Monoclonal antibody 2A11

Pending

Nonindustrial Source

Small Cell Lung Carcinoma

68Ga-sarabesin-3

68Ga-SB-3

Pending

Zentralklinik Bad Berka, Erasmus Universiteit Rotterdam

Prostatic Neoplasms

RC-3095

D-21663, RC-3095

Discontinued

Tulane University

Small Cell Lung Carcinoma, Prostatic Neoplasms