ROBO4
Synonyms
Magic roundabout, ECSM4, Roundabout Guidance Receptor 4, Roundabout, Axon Guidance Receptor, Homolog 4, Roundabout, Axon Guidance Receptor, Homolog 4 (Drosophila), MRB, FLJ20798, AOVD3, Roundabout Homolog 4, Magic Roundabout, Roundabout Homolog 4 (Drosophila),Description
Roundabout homolog 4 (ROBO4) is the receptor for Slit proteins, at least for SLIT2, and seems to be involved in angiogenesis and vascular patterning. It may mediate the inhibition of primary endothelial cell migration by Slit proteins and be involved in the maintenance of endothelial barrier organization and function .
KO Status
F1 (+/-)
Drug Information
Launched drugs: 0
Drugs in clinical trials: 0
Drug Name
Code
Phase
Company
Indications
Clinical Trials
BI-1910
BI-1910
Preclinical
Bioinvent International
Solid tumours
IPR-1110
IPR 1110
Preclinical
Neoplasms
MNPR-101
huATN-658
Preclinical
Monopar Therapeutics Inc
Neoplasms
Nidanilimab
CAN-04
Phase 2 Clinical
Lund University Foundation
Squamous Cell Carcinoma of Head and Neck, Pancreatic Neoplasms, Triple Negative Breast Neoplasms, Carcinoma, Transitional Cell, Breast Neoplasms, Colorectal Neoplasms, Carcinoma, Pancreatic Ductal, Carcinoma, Non-Small-Cell Lung, Melanoma
HLX-71
HLX-71
Phase 1 Clinical
Hengenix Biotech Inc
Coronavirus Disease 2019 (COVID-19)