Generation of TCR-like fully human antibodies against HLA-antigen-peptide complexes using HLA transgenic RenMice


  • We describe an HLA transgenic mouse that acquires fully human TCR mimic antibodies through a proprietary immunization procedure.
  • Beacon on-chips screening and high-throughput binding validation accelerate antibody discovery.
  • Diversified antibody sequences ensure the screening of antibodies with high specificity and high affinity.