AACR 2022: Identifying New Therapeutic Antibodies Using Knockout Mice Expressing Human Immunoglobulin Variable Domain Genes

In conclusion, the RenMice™  HiTS (Hyperimmune Target Specific) Platform enables accelerated identification of fully human antibodies with increased diversity of antibody paratopes and species cross-reactivity. The RenMice™  HiTS Program is focusing on identifying more first-in-class drug targets.